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.intro-grid{display:grid;grid-template-columns:1fr 1fr 1.5fr;background:white;border:1px solid var(--line);border-radius:10px;margin:22px 0;overflow:hidden}.metric{padding:20px 24px;border-right:1px solid var(--line)}.metric:last-child{border:0}.metric strong{display:block;font-size:28px;line-height:1.2}.metric span{display:block;color:var(--muted);font-size:14px;margin-top:7px}.safety{border-left:5px solid #a76418;background:#fff8e9;padding:19px 23px;font-size:15px;border-radius:5px}.contents{display:flex;gap:10px 19px;flex-wrap:wrap;padding:20px 0;font-size:14px;border-bottom:1px solid var(--line)}
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.study{padding:28px 0;border-top:1px solid var(--line);margin-top:24px}.study:last-child{padding-bottom:0}.study-top{display:flex;align-items:center;justify-content:space-between;gap:12px;flex-wrap:wrap}.study-top a{font-size:13px}.study h3{font-size:25px;max-width:800px;margin:16px 0 8px}.study p{max-width:900px}.tag{font-size:11px;letter-spacing:.055em;font-weight:bold;display:inline-block;padding:5px 9px;border-radius:4px}.preclinical{color:#684518;background:#f9edcf}.model{color:#245679;background:#e5eff7}.human{color:#245540;background:#e4f2e9}.negative{color:#7e3333;background:#fae9e6}.sponsor{color:#69497f;background:#efe8f7}.mixed{color:#5b5232;background:#f0eedf}
.two-column{display:grid;grid-template-columns:1fr 1fr;gap:28px}.table-wrap{overflow-x:auto;margin:20px 0;border:1px solid var(--line);border-radius:7px}table{width:100%;border-collapse:collapse;font-size:15px}caption{text-align:left;padding:14px 16px;font-size:13px;color:var(--muted)}th,td{text-align:left;vertical-align:top;padding:15px;border-top:1px solid var(--line);min-width:155px}thead th{background:#eff5f6;color:var(--ink)}tbody th{font-weight:bold;width:23%}.criteria-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:15px}.criteria-grid article{padding:19px 21px;background:#f2f6f7;border-radius:7px;border-top:3px solid #76a9ad}.criteria-grid h3{font-size:19px}.criteria-grid p{font-size:15px}.glossary{display:grid;grid-template-columns:180px 1fr;gap:14px 22px}.glossary dt{font-weight:bold}.glossary dd{margin:0}.text-link{font-weight:bold;display:inline-block;margin-top:12px}
.references{padding-left:25px}.references li{padding:12px 4px 17px;border-bottom:1px solid var(--line)}.references li:last-child{border:0}.references p{font-size:14px;color:var(--muted);margin:7px 0 0}.references strong{font-size:15px}footer{padding:24px 0;color:var(--muted);font-size:14px}
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